Research Physician / Physician Assistant Muscle Diseases Research Team

We are looking for a motivated research physician to join our team within the Radboudumc Expertise Center for Muscle Diseases. You will become part of the Muscle Diseases Research Team, which focuses on clinical studies into innovative (mostly genetic) treatments for rare, hereditary muscle diseases such as FSHD and myotonic dystrophy.

The focus of your role lies on the medical supervision of clinical trial participants, in close collaboration with principal investigators, research nurses, and research coordinators. You will be intensively involved in setting up and conducting these studies, including the medical assessment of participants, interpreting research results, and monitoring safety and protocol adherence.

In addition to this core set of tasks, there is plenty of room to further shape your role in consultation, depending on your interests and background. For example, if you want to delve deeper into substantive research or provide education, we would be happy to explore the possibilities together.

What will you do?

• Clinical assessment of study participants.
• You assess various test results performed within the framework of the research and signal clinical abnormalities in a timely manner.
• You interpret medical results and report on them in consultation with the principal investigator of the study.
• You discuss medical issues with the medical monitor and/or principal investigator.
• You follow training, sometimes also abroad, which is necessary for the execution of the studies.
• You ensure the performance of observations, data collection, and recording, with an emphasis on medical procedures (such as inquiring about symptoms, physical examination, and specific study procedures) within established research protocols.
• You assess whether participants may (continue to) use study medication.
• You coordinate the reporting of (S)AEs and Medical Events of Special Interest (MESIs).

Do you want to contribute to cutting-edge research and work in an inspiring environment? Then apply today and become part of our team!

You will be appointed to the Neurology department and will be part of the Radboudumc Expertise Center for Muscle Diseases, where we provide care at the highest level. We are proud to be part of the European expertise center for muscle diseases (EURO-NMD), and are actively involved in groundbreaking research into the effectiveness of new medicines.

Our field never stands still: research into new treatments is constantly being conducted. Within our center, we conduct several international multicenter drug trials, with a specific focus on children and teenagers with Duchenne disease, and adults with facioscapulohumeral muscular dystrophy (FSHD) and myotonic dystrophy.

As a member of the Muscle Diseases Research Team, you will work closely with research coordinators from the Rehabilitation and Neurology departments and a team of driven research nurses. You will be part of a professional and collegial team in which collaboration, openness, and a collective pursuit of quality are central. Together, you ensure the execution of drug trials, and there is also the possibility to be involved in other scientific studies, such as natural history studies.

What makes us unique is our person-centered approach: we do everything we can to minimize the burden on participants and their environment, and ensure that every visit goes as pleasantly and worry-free as possible.

The Muscle Diseases Center of Radboudumc offers an inspiring working environment, where patients of all ages receive care from a multidisciplinary team of experts. Within our center, we possess specialist knowledge of various muscle diseases, including Duchenne and Becker muscular dystrophy (DBMD), facioscapulohumeral dystrophy (FSHD), myotonic dystrophy (MD), and congenital myopathies (CM).

You work accurately and responsibly, enjoy intensive collaboration with patients and colleagues, and are enthusiastic about clinical research. You possess excellent communication skills and feel at home both independently and within a team. Additionally, you like to contribute to the further development of a strong team. You have excellent organizational skills.

You are critical, stress-resistant, flexible, and proactive. You also know how to maintain an overview, even in busy situations. You think in solutions, enjoy exploring unknown territory, and are constantly looking for opportunities to improve processes.

We are open to different profiles

• A general practitioner wishing to gain experience in clinical-scientific research.
• A physician with PhD experience or clinical experience, looking for depth or a new direction.
• A graduated and registered Physician Assistant (PA) with an interest in clinical-scientific research and care for patients with rare muscle diseases.
  
  Specific experience in neurology or muscle diseases is not a requirement. Affinity with patient-centered research and interest in rare diseases is.

Above all, your passion for the profession, your commitment to patient-centered research, and your interest in innovative treatments for rare diseases make you a valuable addition to our team.

Additionally, you recognize yourself in the profile below:

• You are a graduated physician and BIG-registered, or a graduated and registered Physician Assistant (PA).
• You have a strong interest in patient-related (clinical) research and are motivated to further develop your knowledge in this field.
• Affinity with care and research for people with rare hereditary muscle diseases is a plus.
• You have completed the ICH/GCP or BROK course, or are willing to follow it.
• You have a good command of both the Dutch and English languages.
• You are ICT-proficient and have experience with Word and Excel.
  

• The first interviews will take place on December 1, 2026. It would be helpful if you take this into account.
• A Certificate of Conduct (VOG) is required for this position.

Employment conditions
The salary is determined based on education, experience, and job profile. For the position of research physician, scaling in scale 10 applies. Candidates applying as Physician Assistant are scaled according to the employment conditions and salary scale applicable to this position (scale 10M).

We are recruiting for this vacancy ourselves. We do not appreciate acquisition; however, sharing within your network is welcome.